Efficacy of triple-negative breast cancer treatments
a systematic review
DOI:
https://doi.org/10.61695/rcs.v2i1.26Palabras clave:
Triple-negative breast cancer, Treatment, EfficacyResumen
Triple-negative breast cancer (TNBC) is a subtype caused by a mutation in the BRCA 1 gene, which is responsible for the components of DNA. In this histological type of cancer, estrogen, progesterone, and HER2 protein receptors are absent, making it very aggressive, with great metastatic potential and a lack of therapies, requiring surgical intervention and a neoadjuvant approach. In this way, the study aims to list and discuss the effectiveness of different treatments for triple-negative breast cancer. This is a systematic review of the effectiveness of treatments for triple-negative breast cancer. A search was carried out in the U.S National Library of Medicine (PubMed) database, with articles searched between 2018 and November 8, 2023, with the descriptors: (“triple-negative breast cancer” OR “triple-negative breast neoplasm”) And treatment AND efficiency AND effectiveness. 203 studies were gathered, 200 of which were excluded based on the exclusion criteria. Studies were analyzed resulting from the predictions of the use of SWE images and their effect on TNBC, in addition to the efficacy and prognosis of neoadjuvant chemotherapy (NAC) in conjunction with breast-conserving surgery, as well as the creation of an evaluative measurement index of the efficacy of neoadjuvant systemic therapy. Considering the analysis of these studies, the transition to breast-conserving surgery combined with NAC represents the best strategy, with superior operational results. However, there is a need for more in-depth evaluations regarding research in TNBC treatment.
Descargas
Citas
Abbas AK, Aster JC, Kumar VR. Basic pathology. 9. ed. Rio de Janeiro: Guanabara Koogan, 2021.
Chang C, Liu X, Qian L,Tang S, Zhang H, Zheng D, Zhou J, Zhou S. Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple-negative breast cancers to predict clinical treatment. Bioact Mater, 2022; 22:567–587. https://doi.org/10.1016/j.bioactmat.2022.10.025
Chen R, He J, Huang X, Shi W, Shi X, Wan X, Wang J, Wang S, Wang Y, Xu H, Xu L, Xu Y, Zha X, Zhang W. Volume change rate before and after neoadjuvant systemic therapy of breast cancer is an efficacious evaluation index to predict pathological complete response. Front Oncol, 2023;13:910869. https://doi.org/10.3389/fonc.2023.910869
Instituto Nacional de Câncer José Alencar Gomes da Silva. October Pink 2023. Rio de Janeiro: INCA, 2023. Available at: https://www.gov.br/inca/pt-br/assuntos/campanhas/2023/outubro-rosa
Liu W, Wang P, Wang Z, Zhang H, Zhang X. Breast-conserving surgery in triple-negative breast cancer: a retrospective cohort study. Evid Based Complement Alternat Med. 2023; 5431563. https://doi.org/10.1155/2023/5431563
Pinto M. Triple negative breast carcinoma: correlations and therapeutics [Undergraduate Thesis]. Florianópolis: Universidade Federal de Santa Catarina, 2019. Available at: https://repositorio.ufsc.br/bitstream/handle/123456789/203318/TCC%20Micheli%20B.%20Pinto%2015100328.pdf?sequence=2&isAllowed=y
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2024 Hannara Andrade Gabina de Oliveira, Calebe Vitor Guimarães Catarino, Giordano Bruno Araújo Bonfim, Henrique de Araújo Pereira Neto, Ilanna Moraes Carvalho, Ilmarya Barros Pereira, Isabela Silva Nakata, Dayana Dourado de Oliveira Costa
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
