O uso de biomarcadores de estresse oxidativo no estudo de exposição a agrotóxicos
uma revisão
DOI:
https://doi.org/10.61695/rcs.v1i1.2Palavras-chave:
Saúde Ocupacional, Agrotóxicos, Estrese oxidativo, Biomarcadores, BiomonitoramentoResumo
O uso extensivo de compostos químicos na agricultura tem sido relacionado com a exposição ocupacional de agricultores, além da degradação e contaminação ambiental. Tais fatores, podem potencializar o desequilíbrio entre os compostos oxidantes e antioxidantes, permitindo, assim, a produção excessiva de espécies reativas de oxigênio, o que pode causar danos às biomoléculas e originar diversas doenças, dentre elas o Alzheimer e o câncer. Para correlacionar os efeitos tóxicos à exposição aos agrotóxicos os biomarcadores de estresse oxidativo se tornaram alternativa viável, pois são moléculas mais estáveis, específicas e sensíveis, com maior capacidade de mensuração, podendo expressar processos biológicos normais e patológicos, ou respostas farmacológicas a intervenções terapêuticas. Assim, este trabalho teve como objetivo avaliar a aplicação do uso de biomarcadores de estresse oxidativo no estudo da exposição aos agrotóxicos. Após a revisão da literatura em bases de dados online (PubMed, Science Direct, Web of Science e Google Scholar), foi possível concluir que diferentes parâmetros têm sido usados como ferramentas fundamentais durante todas as etapas da avaliação de risco após a exposição a agrotóxicos.
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Copyright (c) 2023 Heberson Teixeira da Silva, Kimberly Silva Souza, Kaynara Trevisan, Dilceu Silveira Tolentino Júnior, Tales Alexandre Aversi-Ferreira
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